This. I was admitted by ambulance to A&E the morning after a day procedure went wrong and I was told to go home. The pain was unbelievable (I was developing peritonitis and was busy working on an acute kidney injury). They gave me a shot of morphine which had no effect, nothing, nada, niet. So, when I made my views on being in pain clear, out came the pethadine. I was given three injections over a three day period. No feckin’ idea what went on, but it was great. Much better than being in pain.
In my case the appropriate emoji is not . That stuff is dynamite.
My mother was a tooth puller. I speak from years of experience. Powerful drugs, in copious quantities, are the only possible option. Before. During. And After.